Gleason's Gielinor Guide

Potions are consumable items that have a variety of different effects and bonuses. Players are able to make most of them at various levels with the Herblore skill using herbs and other ingredients.

Most potions act as a temporary skill boost, but some have other effects, like curing poison or providing dragonfire protection. A player must add a secondary ingredient to the unfinished potion, finishing the potion completely. A newly finished vial of potion contains three (3) doses of the potion. Some higher-level potions require a vial of coconut milk or blood to be used instead of water.

Wearing an amulet of chemistry gives a 5% chance of creating a four (4) dose potion instead. A charged alchemist's amulet increases this chance to 15%. Prescription goggles give players a 10% chance to not consume a secondary ingredients when mixing potions. These items can be useful for conserving resources on Ironman accounts or for potions with rare or expensive ingredients.

Similar to the delay after eating food, drinking a non-barbarian potion will delay your next potion consumption by 3 ticks (1.8 seconds). Notably, food and potions do not share the same timer, meaning it is possible to eat a piece of food then drink a potion in the same tick. Note that drinking barbarian mixes use the same timer that eating food does.

F2P potions

Strength potion: obtainable by giving the Apothecary 5 coins, one limpwurt root and Red spiders' eggs.

Energy potion: obtainable by giving the Apothecary one chocolate dust and two limpwurt roots.

Antipoison: obtainable by giving the Apothecary 5 coins, one limpwurt root and Cadava berries.

Regular potions

For information about the cost per experience, see Calculator:Herblore/Potions

Level		Experience			Secondary Ingredient		Notes
3	Imp repellent	5	Anchovy oil	Flowers (various)	N/A		Used in impling hunting and to make impling jars. Many types of flowers can be used to make it.
3	Attack potion	25	Vial of water	Guam leaf		Eye of newt	Temporarily raises Attack level by 10% + 3.
5	Antipoison	37.5	Vial of water	Marrentill		Unicorn horn dust	Cures poison and provides immunity for 90 seconds.
8	Relicym's balm	40	Vial of water	Rogue's purse		Snake weed	Cures disease. Requires partial completion of Zogre Flesh Eaters.
12	Strength potion	50	Vial of water	Tarromin		Limpwurt root	Temporarily raises Strength level by 10% + 3.
15	Serum 207	50	Vial of water	Tarromin		Ashes	Temporarily cures Afflicted NPCs in Mort'ton Learned and required in Shades of Mort'ton.
18	Guthix rest tea	59	Cup of hot water	Harralander		Guam leaves x2 Marrentill	Cures poison, restores some run energy, and heals 5 Hitpoints (with the ability to overheal). The herbs can be mixed in any order. Requires partial completion of One Small Favour.
22	Compost potion	60	Vial of water	Harralander		Volcanic ash	Used to convert Compost into Supercompost.
22	Restore potion	62.5	Vial of water	Harralander		Red spiders' eggs	Restores combat-related stats back to normal by 30% of level plus 10. Does not restore Hitpoints or Prayer points.
22	Guthix balance	50 (2 × 25)	Restore potion	Garlic		Silver dust	Used against Vampyre Juvinates and Vampyre Juveniles, particularly in the Temple Trekking minigame.
25	Blamish oil	80	Vial of water	Harralander		Blamish snail slime	Used to make oily fishing rods during the Heroes' Quest.
26	Energy potion	67.5	Vial of water	Harralander		Chocolate dust	Restores 15% run energy.
30	Defence potion	75	Vial of water	Ranarr weed		White berries	Temporarily raises Defence level by 10% + 3.
34	Agility potion	80	Vial of water	Toadflax		Toad's legs	Temporarily raises Agility level by 3.
36	Combat potion	84	Vial of water	Harralander		Goat horn dust	Effect of both Attack potion and Strength potion.
38	Prayer potion	87.5	Vial of water	Ranarr weed		Snape grass	Restores 25% of the player's total Prayer level plus 7. Effect increased by Holy wrench.
45	Super attack	100	Vial of water	Irit leaf		Eye of newt	Temporarily increases Attack level by 15% + 5.
47	Goblin potion	55	Vial of water	Toadflax		Pharmakos berries	Transforms the player into a goblin. Not tradeable. Made during the Land of the Goblins quest and is usable only within the Goblin Cave and Goblin Temple.
48	Superantipoison	106.3	Vial of water	Irit leaf		Unicorn horn dust	Cures poison and provides immunity for 6 minutes.
49	Anti-odour salt	11	Elkhorn coral	Crab paste	N/A		Automatically smokes Hunter traps when in the inventory.
50	Fishing potion	112.5	Vial of water	Avantoe		Snape grass	Temporarily raises Fishing level by 3.
52	Super energy	117.5	Vial of water	Avantoe		Mort myre fungus	Restores 20% run energy.
52	Shrink-me-quick	6	Vial of water	Tarromin		Shrunk ogleroot	Reduces player size during the Grim Tales quest.
53	Hunter potion	120	Vial of water	Avantoe		Kebbit teeth dust	Temporarily raises Hunter level by 3. Kebbit teeth are obtained by deadfall trapping Sabre-Toothed Kebbits.
54	Goading potion	132	Vial of water	Harralander		Aldarium	Causes aggression of all monsters within a 9x9 area surrounding the player.
55	Super strength	125	Vial of water	Kwuarm		Limpwurt root	Temporarily raises Strength level by 15% + 5.
56	Haemostatic dressing	127	Vial of water	Elkhorn coral		Squid paste Cotton yarn	Cures bleed, also heals 5 Hitpoints if bleed is cured.
57	Magic essence	130	Vial of water	Star flower		Gorak claw powder	Temporarily raises Magic level by 3. Not tradeable. Made during Fairytale II - Cure a Queen quest, and components are only available via the Fairy rings.
58	Prayer regeneration potion	132	Vial of water	Huasca		Aldarium	Restores 1 Prayer point every 12 ticks for 8 minutes, restoring a total of 66 Prayer points per dose.
60	Weapon poison	137.5	Vial of water	Kwuarm		Dragon scale dust	For use on arrows, daggers, spears, hastae, javelins, darts, knives, and bolts. Poison starts at 4 damage for melee weapons and 2 damage for ranged weapons.
62	Super fishing potion	140.5	Vial of water	Pillar coral		Haddock eye	Temporarily raises Fishing level by 6.
63	Super restore	142.5	Vial of water	Snapdragon		Red spiders' eggs	Restores all stats (except hitpoints) by 25% + 8.
65	Sanfew serum	192 (57 + 63 + 72)	Super restore	Unicorn horn dust		Snake weed Nail beast nails	Sanfew Serum combines the properties of super restore, superantipoison, and relicym's balm potions all in one. Partial experience is given for each addition of one of the secondary ingredients in this potion.
66	Super defence	150	Vial of water	Cadantine		White berries	Temporarily increases Defence level by 15% + 5.
66	Extreme energy potion	84 (4 × 21)	Super energy	Yellow fin	N/A		Restores 40% run energy. One yellow fin is required per dose.
67	Super hunter potion	154	Vial of water	Pillar coral		Crab paste	Temporarily raises Hunter level by 6.
68	Antidote+	155	Coconut milk	Toadflax		Yew roots	Cures and gives immunity to poison for 9 minutes.
69	Antifire potion	157.5	Vial of water	Lantadyme		Dragon scale dust	Provides some resistance to dragonfire. Can be used with an anti-dragonfire shield to completely prevent dragonfire damage. Each dose lasts about 6 minutes.
70	Divine super attack potion	2 (4 × 0.5)	Super attack	Crystal dust	N/A		Boosts the same as a super attack whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
70	Divine super defence potion	2 (4 × 0.5)	Super defence	Crystal dust	N/A		Boosts the same as a super defence whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
70	Divine super strength potion	2 (4 × 0.5)	Super strength	Crystal dust	N/A		Boosts the same as a super strength whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
72	Ranging potion	162.5	Vial of water	Dwarf weed		Wine of Zamorak	Temporarily increases Ranged level by 10% + 4.
73	Weapon poison+	190	Coconut milk	Cactus spine		Red spiders' eggs	For use on arrows, daggers, spears, hastae, javelins, darts, knives, and bolts. Poison starts at 5 damage for melee weapons and 3 damage for ranged weapons.
74	Divine ranging potion	2 (4 × 0.5)	Ranging potion	Crystal dust	N/A		Boosts the same as a ranging potion whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
76	Magic potion	172.5	Vial of water	Lantadyme		Potato cactus	Temporarily raises Magic level by 4.
77	Stamina potion	102 (4 × 25.5)	Super energy	Amylase crystal	N/A		Stamina potions restore 20% run energy and reduce the rate of energy depletion by 70% for 2 minutes. One amylase crystal is required per dose.
78	Zamorak brew	175	Vial of water	Torstol		Jangerberries	Boosts Strength by 12% + 2 and Attack by 20% + 2, but lowers Defence and remaining Hitpoints by 10% + 2.
78	Divine magic potion	2 (4 × 0.5)	Magic potion	Crystal dust	N/A		Boosts the same as a magic potion whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
79	Antidote++	177.5	Coconut milk	Irit leaf		Magic roots	Drinking two doses of antidote++ will cure venom. The first dose reduces the venom to poison and the second removes the poison. In addition, it provides up to 36 seconds immunity to venom upon drinking it. If only poisoned, only one dose is required to cure poison.
80	Bastion potion	155	Vial of blood	Cadantine		Wine of Zamorak	Temporarily increases Ranged by 10% + 4 and Defence by 15% + 5.
80	Battlemage potion	155	Vial of blood	Cadantine		Potato cactus	Temporarily increases Magic by 4 and Defence by 15% + 5.
81	Saradomin brew	180	Vial of water	Toadflax		Crushed nest	Boosts Defence and Hitpoints but lowers Attack, Strength, Magic, and Ranged.
81	Surge potion	185	Vial of water	Torstol		Demonic tallow	Restores 25% Special attack energy, can only be drunk once every five minutes.
82	Weapon poison++	190	Coconut milk	Cave nightshade		Poison ivy berries	For use on arrows, daggers, spears, hastae, javelins, darts, knives, and bolts. Poison starts at 6 damage for melee weapons and 4 damage for ranged weapons.
84	Extended antifire	110 (4 × 27.5)	Antifire potion	Lava scale shard	N/A		Provides some resistance to dragonfire. Each dose lasts about 12 minutes. One shard is required per dose.
85	Ancient brew	190	Vial of water	Dwarf weed		Nihil dust	Boosts Magic and restores prayer points but lowers Attack, Strength, and Defence.
85	Extended stamina potion	110 (4 × 27.5)	Stamina potion	Marlin scales	N/A		Restores 40% run energy and reduce the rate of energy depletion by 70% for 4 minutes. One marlin scale is required per dose.
86	Divine bastion potion	2 (4 × 0.5)	Bastion potion	Crystal dust	N/A		Boosts the same as a bastion potion whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
86	Divine battlemage potion	2 (4 × 0.5)	Battlemage potion	Crystal dust	N/A		Boosts the same as a battlemage potion whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
87	Anti-venom	120 (4 × 30)	Antidote++	Zulrah's scales	N/A		Instantly cures venom. Five scales are required per dose.
88	Menaphite remedy	200	Vial of water	Dwarf weed		Lily of the Sands	Restores 6 + 16% of the player's combat stats every 15 seconds, over the course of five minutes.
89	Armadyl brew	205	Vial of water	Umbral coral		Rainbow crab paste	Boosts Ranged and Hitpoints but lowers Attack, Strength, Defence, and Magic.
90	Super combat potion	150	Super attack Super strength Super defence	Torstol	N/A		Combines the properties of super attack, super strength, and super defence potions.
91	Forgotten brew	145	Ancient brew	Ancient essence	N/A		Upgraded version of an Ancient brew. Boosts Magic by 8% + 3 and restores prayer points by 10% + 2, but lowers Attack, Strength, and Defence by 10% + 2. 20 essence is required per dose.
92	Super antifire potion	130	Antifire potion	Crushed superior dragon bones	N/A		Grants complete immunity to dragonfire for three minutes.
94	Anti-venom+	125	Anti-venom	Torstol	N/A		Instantly cures venom and provides immunity to it for three minutes.
94	Extended anti-venom+	80 (4 x 20)	Anti-venom+	Araxyte venom sac	N/A		Instantly cures venom and provides immunity to it for six minutes.
97	Divine super combat potion	2 (4 × 0.5)	Super combat potion	Crystal dust	N/A		Boosts the same as a super combat potion whilst lasting for 5 minutes with no state degradation. Requires the completion of Song of the Elves to make.
98	Extended super antifire	160 (4 × 40)	Super antifire potion	Lava scale shard	N/A		Grants complete immunity to dragonfire for six minutes. One shard is required per dose.
98	Extended super antifire	180	Extended antifire	Crushed superior dragon bones	N/A

Chambers of Xeric potions

Within the Chambers of Xeric, players can create special kinds of potions using water-filled gourd vials and various potion ingredients found within the raid. The player's Herblore level determines which tier of potion they can make using the ingredients, with each type of potion having a (-), regular, and (+) variant.

Level		Experience	Ingredients
47	Elder (-)	6.5	Golpar Stinkhorn mushroom
59	Elder potion	10
70	Elder (+)	13
47	Twisted (-)	6.5	Golpar Cicely
59	Twisted potion	10
70	Twisted (+)	13
47	Kodai (-)	6.5	Golpar Endarkened juice
59	Kodai potion	10
70	Kodai (+)	13
60	Antipoison (-)	13.5	Noxifer Cicely
75	Antipoison potion	20
90	Antipoison (+)	26.5
52	Revitalisation (-)	13.5	Buchu leaf Stinkhorn mushroom
65	Revitalisation potion	20
78	Revitalisation (+)	26.5
52	Prayer enhance (-)	13.5	Buchu leaf Cicely
65	Prayer enhance	20
78	Prayer enhance (+)	26.5
52	Xeric's aid (-)	13.5	Buchu leaf Endarkened juice
65	Xeric's aid	20
78	Xeric's aid (+)	26.5
60	Overload (-)	33.5	Noxifer Elder (-) Twisted (-) Kodai (-)
75	Overload	50	Noxifer Elder potion Twisted potion Kodai potion
90	Overload (+)	66.5	Noxifer Elder (+) Twisted (+) Kodai (+)

Barbarian Mixes

Barbarian potions can be made by adding roe or caviar to two-dose potions. The barbarian potions will hold two doses that give the same effect as their regular counterparts, as well as restore 3 to 6 Hitpoints per dose.

Note that the default left-click option for roe and caviar is "eat", not "use", making it possible to consume the ingredients by accident instead of using them.

Level		Experience	Eggs needed
4	Attack mix	8	Roe or Caviar
6	Antipoison mix	12	Roe or Caviar
9	Relicym's mix	14	Roe or Caviar
14	Strength mix	17	Roe or Caviar
24	Restore mix	21	Roe or Caviar
29	Energy mix	23	Caviar
33	Defence mix	25	Caviar
37	Agility mix	27	Caviar
40	Combat mix	28	Caviar
42	Prayer mix	29	Caviar
47	Superattack mix	33	Caviar
51	Anti-poison supermix	35	Caviar
53	Fishing mix	38	Caviar
56	Super energy mix	39	Caviar
58	Hunting mix	40	Caviar
59	Super str. mix	42	Caviar
61	Magic essence mix	43	Caviar
67	Super restore mix	48	Caviar
71	Super def. mix	50	Caviar
74	Antidote+ mix	52	Caviar
75	Antifire mix	53	Caviar
80	Ranging mix	54	Caviar
83	Magic mix	57	Caviar
85	Zamorak mix	58	Caviar
86	Stamina mix	60	Caviar
91	Extended antifire mix	61	Caviar
92	Ancient mix	63	Caviar
98	Super antifire mix	70	Caviar
99	Extended super antifire mix	78	Caviar

Varlamorian potions

Varlamorian potions are not drinkable but are used to fulfil orders in the Mastering Mixology minigame.

Base		Combination	Points				Level	XP
Base		Combination	Mox	Aga	Lye	Total	Level	XP
	Alco-AugmentAtor (AAA)		0	20	0	20	60	190
	Mammoth-Might Mix (MMM)		20	0	0	20	60	190
	LipLack Liquor (LLL)		0	0	20	20	60	190
	Mystic Mana Amalgam (MMA)		20	10	0	30	63	215
	Marley's MoonLight (MML)		20	0	10	30	66	240
	Azure Aura Mix (AAM)		10	20	0	30	69	265
	AquaLux Amalgam (ALA)		0	20	10	30	72	290
	MegaLite Liquid (MLL)		10	0	20	30	75	315
	Anti-Leech Lotion (ALL)		0	10	20	30	78	340
	MixALot (MAL)		20	20	20	60	81	365

	Points	Level	XP
Alco-AugmentAtor (AAA)	10 Aga	60	63
Mammoth-Might Mix (MMM)	10 Mox	60	63
LipLack Liquor (LLL)	10 Lye	60	63
Mystic Mana Amalgam (MMA)	10 Aga	63	72
Marley's MoonLight (MML)	10 Lye	66	80
Azure Aura Mix (AAM)	10 Aga	69	88
AquaLux Amalgam (ALA)	10 Lye	72	96
MegaLite Liquid (MLL)	10 Lye	75	105
Anti-Leech Lotion (ALL)	10 Lye	78	113
MixALot (MAL)	10 Lye	81	122

Quest potions

Level		Quest	Potion Base			Secondary Ingredient		Notes
N/A	Cadava potion	Romeo & Juliet	N/A		Cadava berries	N/A		You can get this potion by giving Cadava berries to the Apothecary in Varrock. It cannot be made.
N/A	Potion of Sealegs	Bone Voyage		Marrentill potion (unf)	Vodka x2	N/A		You can get this potion by giving a Marrentill potion (unf) and two Vodka to the Apothecary in Varrock. It cannot be made.
N/A	Potion (A Taste of Hope)	A Taste of Hope		Vial of water	Mysterious herb		Mysterious crushed meat
N/A	Sulphur potion	A Kingdom Divided	or	Defence potion(3) or Defence potion(4)	Volcanic sulphur	N/A		This potion is enchanted into a shielding potion by the Tasakaal.
1	Bravery potion	Legends' Quest		Vial of water	Ardrigal		Snake weed	This potion is drunk to gain unlimited access to the dark cave in the Kharazi Dungeon. You can remake it after the quest.
14	Potion (Watchtower)	Watchtower		Vial of water	Guam leaf		Jangerberries Ground bat bones	This potion needs to be enchanted by the Watchtower Wizard to be turned into a Magic ogre potion. This potion is used to kill ogre shamans in the Ogre Enclave below Gu'Tanoth. It cannot be made after the quest is complete.
31	Troll potion	Eadgar's Ruse		Vial of water	Ranarr weed		Ground thistle	This potion is used to find out about goutweed from Burntmeat. You cannot make this after the quest.
47	Goblin potion	Land of the Goblins		Vial of water	Toadflax		Pharmakos berries	This potion is only usable in within the Goblin Cave and Goblin Temple and will transform the player into a goblin. You can remake it after the quest.
52	Shrink-me-quick	Grim Tales		Vial of water	Tarromin		Shrunk ogleroot	This potion will shrink a player to allow them to go through the mouse hole in the witch's house in Taverley. This potion can still be made and used after the quest.
57	Magic essence	Fairytale II - Cure a Queen		Vial of water	Star flower		Gorak claw powder	This potion can also be used to get a +3 boost to Magic.
62	Strangler serum	Desert Treasure II - The Fallen Empire		Unfinished serum	Korbal herb		Argian berries	Drinking this potion prevents The Strangler from infecting the player.
70	Inversion potion	Song of the Elves		Vial of water	Elder cadantine		Crystal dust (Song of the Elves)